Päivitys 17.4. 2014
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- Abstract
- 1. Introduction
- 2 Biological activities of MMPs and cardiovascular diseases
- 3 General structural features of MMPs
- 4 MMPs and their domain arrangements
- 5 Three-dimensional (3D) structures of MMPs
- 6 Activation of proMMPs
- 7 The role of non-catalytic domain of MMPs in substrate specificity: An insight into collagenolysis
- 8 The role of hemopexin domains in proMMP-2 activation by MT1-MMP (MMP-14)
- 9 Palmitoylation of MT1-MMP and cell migration
- 10 Endogenous inhibitors of MMPs
- 11 Inhibition mechanism of TIMPs and TIMP variants
- 12 Conclusions and future prospects
- Acknowledgements
- Footnotes
- References
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