TIMP- 1 Väitöskirjoja

Sökning: "tissue inhibitor of metalloproteinase 1 TIMP-1"

Visar resultat 6 - 10 av 10 avhandlingar innehållade orden tissue inhibitor of metalloproteinase 1 TIMP-1.

1. 6. Inflammatory Markers, Respiratory Diseases, Lung Function and Associated Gender Differences

   Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis
   Författare :Inga Sif Ólafsdóttir; Uppsala universitet.; [2011]
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; C-reactive protein; matrix metalloproteinase-9; tissue inhibitor of metalloproteinase-1; COPD; FEV1; FVC; lung function; systemic inflammation; gender differences; Lung Medicine; Lungmedicin;
   Sammanfattning : Systemic inflammation is associated with impaired lung function. Inflammation is part of asthma and chronic obstructive pulmonary disease (COPD), but the local and systemic inflammatory pattern differs. LÄS MER

3. 7. Cerebral white matter changes in patients with cognitive impairment - clinical and pathophysiological aspects

   Detta är en avhandling från University of Gothenburg
   Författare :Michael Jonsson; Göteborgs universitet.; University of Gothenburg.; [2012]
   Nyckelord :white matter changes; vascular factors; cognitive impairment; neuropsychiatric symptoms; cerebrospinal fluid biomarkers; demyelination; axonal degeneration;
   Sammanfattning : Cerebral white matter changes (WMC), detected with computed tomography (CT) or magnetic resonance imaging (MRI), represent a common condition in elderly people. However, the prognostic, symptomatological and biochemical constituents of WMC are only partially known. LÄS MER

4. 8. Inflammation and cortisol response i coronary artery disease

   Detta är en avhandling från Linköping : Linköping University Electronic Press
   Författare :Johnny Nijm; Linköpings universitet.; Linköpings universitet.; [2008]
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Coronary artery disease; MEDICINE Dermatology and venerology; clinical genetics; internal medicine Internal medicine Cardiology; MEDICIN Dermatologi och venerologi; klinisk genetik; invärtesmedicin Invärtesmedicin Kardiologi; MEDICINE Dermatology and venerology; clinical genetics; internal medicine Internal medicine; MEDICIN Dermatologi och venerologi; klinisk genetik; invärtesmedicin Invärtesmedicin;
   Sammanfattning : Atherosclerosis is characterized by a chronic inflammation, involving autoimmune components, in the arterial wall. An increase in proinflammatory activity relative to anti-inflammatory activity is considered to cause a progression of the disease towards plaque instability and risk of atherothrombotic events, such as acute coronary syndrome (ACS). LÄS MER

5. 9. Systemic sclerosis : vascular, pulmonary and immunological aspects

   Detta är en avhandling från Umeå : Reumatologi
   Författare :Grethe Neumann Andersen; Umeå universitet.; [2008]
   Nyckelord :Systemic sclerosis; interstitial lung disease; MMP-9; Th1 Th2; transcription factors; NO; iNOS; E-selectin; endothelium-dependent dilation; endothelium-independent dilation.; MEDICINE Dermatology and venerology; clinical genetics; internal medicine Internal medicine Rheumatology; MEDICIN Dermatologi och venerologi; klinisk genetik; invärtesmedicin Invärtesmedicin Reumatologi;
   Sammanfattning : In systemic sclerosis (SSc), interstitial lung disease (ILD) and engagement of the vascular system lead to increased morbidity and mortality.The aim of this thesis was to elucidate, in a consecutively included cohort of SSc (limited and diffuse) patients (n = 33), the T cell cytokine profile driving the disease in ILD and to explore the role of matrix metalloproteinase 9 (MMP-9) and its inhibitor: tissue inhibitor of metalloproteinase 1 (TIMP-1) in the extracellular matrix (ECM) degrading process leading to fibrous scarring and honey combing. LÄS MER

7. 10. Matrix degrading proteases in the ovary : expression and function

   Detta är en avhandling från Umeå : Medicinsk biokemi och biofysik
   Författare :Patrik Wahlberg; Umeå universitet.; [2004]
   Nyckelord :Biochemistry; ovary; ovulation; corpus luteum; plasminogen; PA; MMP; rat; mouse; Biokemi; MEDICINE Chemistry Biochemistry; MEDICIN Kemi Biokemi; Medical Biochemistry; medicinsk biokemi;
   Sammanfattning : Extracellular matrix degrading proteases from the plasminogen (plg) activator (PA) and the matrix metalloproteinase (MMP) systems have been implicated as important mediators of ovulation and corpus luteum (CL) formation and regression. The aim of this thesis was to investigate the expression and regulation of PAs and MMPs in the ovary and to examine their functional roles for CL formation and function. LÄS MER