ACE angiotensin I converting enzyme [ Homo sapiens (human)
]
Gene ID: 1636, updated on 13-Nov-201617q23.3.
- Official Full Name
- angiotensin I converting enzymeprovided by HGNC
- Gene type
- protein coding
- Organism
- Homo sapiens
- Also known as
- DCP; ACE1; DCP1; CD143
- Summary
- This gene encodes an enzyme involved in catalyzing the
conversion of angiotensin I into a physiologically active peptide
angiotensin II. Angiotensin II is a potent vasopressor and
aldosterone-stimulating peptide that controls blood pressure and
fluid-electrolyte balance. This enzyme plays a key role in the
renin-angiotensin system. Many studies have associated the presence or
absence of a 287 bp Alu repeat element in this gene with the levels of
circulating enzyme or cardiovascular pathophysiologies. Multiple
alternatively spliced transcript variants encoding different isoforms
have been identified, and two most abundant spliced variants encode the
somatic form and the testicular form, respectively, that are equally
active. [provided by RefSeq, May 2010]
PROTEIN_ Tämä teksti antaa taustaa seuraavien ACEI
lääkkeiden käytölle: captopril, enalapril, lisinopril.
https://www.ncbi.nlm.nih.gov/protein/P12821.1
Inga kommentarer:
Skicka en kommentar